MSM 500 Methyl-Sulfonyl-Methane

Our MSM 500 is a highly concentrated source of the organic Sulfur required for the healthy structure and function of some of the most challenged tissues in our body - our joints, skin, nails and hair.

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MSRP $16.90
SAVE $3.00



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Product Information


Andrew Lessman's MSM 500 delivers a pure, concentrated source of organic Sulfur. MSM is short for Methyl-Sulfonyl-Methane and despite its long name, it is actually a small, easily-absorbed molecule that is ideally built around a central Sulfur molecule. Sulfur is perhaps the most overlooked essential nutrient necessary for maintaining healthy joints, hair, skin and nails. Sulfur plays an essential structural and functional role in joint and connective tissue (cartilage, ligaments and tendons) and it is also essential to creation of the proteins (elastin, keratin and collagen) that comprise our hair, skin and nails. Like so many essential nutrients, Sulfur is removed by modern food processing, making supplementation an important consideration for healthy joints, as well as the attractive appearance of our hair, skin and nails. Our MSM 500 is a highly concentrated source of the organic Sulfur required for the healthy structure and function of some of the most challenged tissues in our body – our joints, skin, nails and hair. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


Serving Size
1 Capsule
Amount Per Serving
Vitamin C (as calcium ascorbate)
50 mg
MSM (as methylsulfonylmethane)
500 mg
* Percent Daily Values (%DV) are based on a 2,000 calorie diet. † Daily Value not established
Other Ingredients: Gelatin capsule.

Suggested Use

Consume one or more capsules daily or as recommended by your physician. As with any dietary supplement, this product is most effective as part of a healthy diet and active lifestyle.

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Customer Reviews

Based on 28 reviews


Self Care, Vee Love Taking well made vitamins
By Amazon, NV on 5/28/2021

Great assistance in combating allergies High doses of MSM were recommended by my primary care physician, in combating my environmental allergies. I used to wake up with dark circles and horribly puffy eyes. 2,000 to 3,000 mg taken throughout the day has tremendously reduced by allergy symptoms. I can now enjoy being outdoors and not 'pay the price' the next day. Sounds like a lot, but 3,000 mg vs terribly swollen eyes and congestion is worth it. My physician swears by it--and after trying it, I believe her!
By Tami, KS on 4/2/2021

Perfect to go with Glucosamine and Chondroitin Started taking Glucosamine and Chondroitin for my joints and was happy with results, except for my left knee. It started getting stiff and sore. Decided to try the MSM and with the first dose my knee pain is gone. These are my results, I feel like these two products together is a good option.
By Kathleen, MI on 11/21/2020

Order these ASAP!!!, JAG2000 After reading a review for a biotin soft gel I was going to buy due to my old biotin being changed a reviewer stated that you shouldn’t take biotin without MSM. So I thought hmmm what is MSM. I looked that product up and I thought thank you universe! I suffer from joint pain and arthritis in my hands. I use to take a methotrexate for it but made my hair come out in handfuls. So I stopped and told my dr. I wasn’t taking it and would live with the pain. I researched and found fish oil would help so off to a big box store to buy it and have been taking it for over 6yrs. Fish oil helps but not 100%.Upon reading the benefits of MSM I ordered Andrew lesserman because I use to take his hair skin and nail supplement which by the way works great for my hair and nails. Not sure about my skin. After taking the MSM coupled with my drug store soft gel biotin I can say this product is amazing. I wish I knew about it 10 years ago. Wow!!! I have flipped my pillow top mattress by myself. I put a new bed skirt on the bed I have lifted cases of water and cleaned and no pain. If I had done these activities prior to taking these I would’ve had to take 3 advil and rest for 3 days after no joke! MSM is now part of my daily intake of supplements. I will never not take it. My hands look great and feel great. I have energy to do housework or whatever and not be concerned about pain following. I only take 1 a day as I wanted to ease into taking it and wanted to make sure my body could handle it along with my other medications and supplements I take. No issues. I may up it to 2 pills a day but for now I only take 1.I have told friends and family about it and they have ordered and thanked me. Why don’t doctors tell us about these type of supplements? Do yourself a favor of you have arthritis or joint pain and order this immediately. You won’t be disappointed. You’re welcome!
By Amazon, NV on 11/21/2020